UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

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PPARGC1A — RPTOR

Pathways - manually collected, often from reviews:

NCI Pathway Database mTOR signaling pathway: mTORC1 complex (MTOR-MLST8-RPTOR) → PGC1A (PPARGC1A) (modification, collaborate) Cunningham et al., Nature 2007
Evidence: mutant phenotype, physical interaction
NCI Pathway Database mTOR signaling pathway: mTORC1 complex (MTOR-MLST8-RPTOR) → mTORC1/PGC1A/YY1 complex (MTOR-MLST8-RPTOR-PPARGC1A-YY1) (modification, collaborate)
Cunningham et al., Nature 2007
Evidence: mutant phenotype, physical interaction
NCI Pathway Database mTOR signaling pathway: YY1 (YY1) → mTORC1/PGC1A/YY1 complex (MTOR-MLST8-RPTOR-PPARGC1A-YY1) (modification, collaborate)
Cunningham et al., Nature 2007
Evidence: mutant phenotype, physical interaction
NCI Pathway Database mTOR signaling pathway: PGC1A (PPARGC1A) → mTORC1/PGC1A/YY1 complex (MTOR-MLST8-RPTOR-PPARGC1A-YY1) (modification, collaborate)
Cunningham et al., Nature 2007
Evidence: mutant phenotype, physical interaction