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BDNF — NTF4

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Bind Interaction: NTF4 — BDNF Robinson et al., Protein Sci 1999*, Robinson et al., Biochemistry 1995*, Radziejewski et al., Biochemistry 1993*
• IRef Bind_translation Interaction: NTF4 — BDNF (x-ray crystallography) Radziejewski et al., Biochemistry 1993*
• IRef Ophid Interaction: NTF4 — BDNF (aggregation, interologs mapping) Brown et al., Bioinformatics 2005

Text-mined interactions from Literome

Numakawa et al., Brain Res 1999 : NGF and NT-3 elicited neurotrophin induced release of glutamate as well as BDNF from the cerebellar granule neurons
Xiong et al., Neuropharmacology 2002 (MAP Kinase Signaling System) : In the present study, brain derived neurotrophic factor (BDNF) mRNA expression is induced by neurotrophin-4/5 ( NT-4/5 ) and by BDNF itself in neocortical neurons ... NT-4/5 significantly augments BDNF protein production, which is also reversed by K252a
Patz et al., Eur J Neurosci 2004 : Here we investigated the mRNA expression level of brain derived neurotrophic factor (BDNF) , neurotrophin-4 (NT-4), NT-3 and nerve growth factor (NGF) as well as the tyrosine receptor kinases TrkB and TrkC receptor in response to BDNF, NT-4 , NT-3 and NGF pulses in organotypic cortex cultures
Bramham et al., J Neurosci 2008 (Synaptic Transmission) : This process of Arc dependent consolidation is activated by the secretory neurotrophin , BDNF
Slipczuk et al., PloS one 2009 : Interestingly, BDNF ASO hindered LTM retention only when given into dorsal CA1 1 h after but not 2 h before training, suggesting that BDNF controls the biphasic requirement of mTOR during LTM consolidation through different mechanisms : an early one involving BDNF already available at the moment of training, and a late one, happening around 3 h post training that needs de novo synthesis of this neurotrophin
Huang et al., Dev Dyn 2010 : Bdnf and Ntf4/5 are expressed in equal amounts at E12.5 in geniculate ganglion, but Bdnf expression increased from E14.5 to birth, whereas Ntf4/5 expression decreased
Apfel et al., Mol Cell Neurosci 1996 : We show here that brain derived neurotrophic factor (BDNF) gene expression in dorsal root ganglia is strongly stimulated in vivo by another neurotrophin , nerve growth factor (NGF)
Nonner et al., J Neurosci 1996 (Hypoglycemia) : However, with very low plating densities ( 2-28 cells/mm2 ) BDNF, NT-3, and NT-4 ( but not NGF ) increased total neuronal survival, and BDNF increased survival of AChE positive neurons