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DCTN3 — TP53
Text-mined interactions from Literome
Naoe et al., Cancer Sci 2006
(Hematologic Neoplasms...) :
Nucleophosmin (NPM) is a nucleolar phosphoprotein that plays multiple roles in ribosome assembly and transport, cytoplasmic-nuclear trafficking,
centrosome duplication and
regulation of
p53
Bergstralh et al., Exp Cell Res 2007
(Lung Neoplasms) :
Mass spectroscopy identified the protein as nucleophosmin/B23 (NPM), a multifunctional protein with diverse roles : ribosome biosynthesis,
p53 regulation , nuclear-cytoplasmic shuttling, and
centrosome duplication
Schäfer et al., Oncogene 1998
:
Our data demonstrate that
p22/PRG1 transcription is
induced by
p53 during p53 dependent cell cycle arrest and apoptosis
Schäfer et al., FEBS Lett 1998
(Carcinoma, Hepatocellular...) :
CAT-reporter gene assays show
transactivation of the human
p22/PRG1 promoter by
p53 in Hep3B cells stably transfected with a temperature-sensitive mutant p53, but not in p53-deficient Hep3B cells
Mantel et al., Blood 1999
(Polyploidy) :
p53 has already been implicated in
centrosome regulation