Gene interactions and pathways from curated databases and text-mining

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DCTN3 — TP53

Text-mined interactions from Literome

Naoe et al., Cancer Sci 2006 (Hematologic Neoplasms...) : Nucleophosmin (NPM) is a nucleolar phosphoprotein that plays multiple roles in ribosome assembly and transport, cytoplasmic-nuclear trafficking, centrosome duplication and regulation of p53
Bergstralh et al., Exp Cell Res 2007 (Lung Neoplasms) : Mass spectroscopy identified the protein as nucleophosmin/B23 (NPM), a multifunctional protein with diverse roles : ribosome biosynthesis, p53 regulation , nuclear-cytoplasmic shuttling, and centrosome duplication
Schäfer et al., Oncogene 1998 : Our data demonstrate that p22/PRG1 transcription is induced by p53 during p53 dependent cell cycle arrest and apoptosis
Schäfer et al., FEBS Lett 1998 (Carcinoma, Hepatocellular...) : CAT-reporter gene assays show transactivation of the human p22/PRG1 promoter by p53 in Hep3B cells stably transfected with a temperature-sensitive mutant p53, but not in p53-deficient Hep3B cells
Mantel et al., Blood 1999 (Polyploidy) : p53 has already been implicated in centrosome regulation