Gene interactions and pathways from curated databases and text-mining

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MAP2K4 — RELA

Text-mined interactions from Literome

Chen et al., J Biol Chem 1999 : Vanadate induction of NF-kappaB involves IkappaB kinase beta and SAPK/ERK kinase 1 in macrophages
Ludwig et al., Cancer Res 2001 (Carcinoma, Medullary...) : RET induced NF-kappaB and IKKbeta activity requires Ras function but does neither involve the classical mitogen activated protein kinase kinase/extracellular signal regulated kinase nor the phosphoinositide 3-kinase/Akt pathways
Chen et al., J Biol Chem 2004 (Crohn Disease) : In this study, we determined that mitogen activated protein kinase kinase transforming growth factor ( TGF)-beta activated kinase 1 (TAK1 ) interacts with Nod2 and is required for Nod2 mediated NF-kappaB activation