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ANGPT2 — ETS1
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Hasegawa et al., Biochem Biophys Res Commun 2004
:
Transcriptional
regulation of human
angiopoietin-2 by transcription factor
Ets-1
Watanabe et al., Am J Pathol 2004
(Anoxia...) :
Dominant negative
Ets-1 inhibited VEGF induced cell proliferation, tube formation, and the expression of neuropilin-1 and
angiopoietin-2
Pearse et al., American journal of physiology. Renal physiology 2008
:
COX-2 inhibition prevented
ETS-1 expression in
response to
ANG II , suggesting that COX-2 is required for ETS-1 induction
Kumar et al., Ren Fail 2010
:
Ang II enhances tubular cell
Ets-1 expression and associated down stream signaling is mediated through AT1 receptors ... In the present study, we evaluated the
effect of
Ang II on the activation of
Ets-1 ( a transcription factor ) in tubular cells ... In in vitro studies,
Ang II enhanced mRNA expression of
Ets-1 by MDCK cells
Hua et al., American journal of physiology. Renal physiology 2012
:
In these studies, we determined that
ANG II induces phosphorylation of
ETS-1 via activation of the type 1 ANG II receptor and that Erk1/2 and Akt/PKB phosphorylation are required for these effects