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HLA-G — IFNG
Text-mined interactions from Literome
Lefebvre et al., J Reprod Immunol 1999
:
We then investigated the
effect of
IFN-gamma on
HLA-G gene expression
Lefebvre et al., Hum Immunol 2000
:
We further show that
IFN-gamma also
upregulates levels of
HLA-G transcripts in TEC primary cultures ... This study provides evidence that
IFN-gamma induction of
HLA-G expression occurs in the human amnion and the thymus, and is mediated at the transcriptional level in these tissues
Hurks et al., Invest Ophthalmol Vis Sci 2001
(Melanoma...) :
Furthermore,
interferon-gamma did not
induce HLA-G expression in the uveal melanoma cell lines
Mitsdoerffer et al., J Neuroimmunol 2005
(Multiple Sclerosis, Relapsing-Remitting) :
Although both IFN-beta and
IFN-gamma strongly
enhance HLA-G1 and HLA-G5 expression by monocytes in vitro, IFN-beta leads to a stronger relative upregulation of HLA-G compared to classical MHC class I molecules than stimulation with IFN-gamma
Morandi et al., Cancer Res 2007
(Neuroblastoma...) :
In 6 of 12 human neuroblastoma cell lines, low
HLA-G surface expression was not
up-regulated by
IFN-gamma
Alegre et al., Hum Immunol 2007
(Pregnancy Complications) :
Monocytes obtained during pregnancy showed a moderately
HLA-G cell surface expression and stimulation with
interferon (IFN)-gamma increased this expression
Blanco et al., Hum Reprod 2008
:
Interferon gamma , a cytokine implicated in the vascular remodelling of the decidua necessary for embryo implantation, also
increased the expression of
HLA-G by DSC ( P < 0.05 )
Yang et al., J Immunol 1996
:
Expression of
HLA-G in human mononuclear phagocytes and selective
induction by
IFN-gamma