Gene interactions and pathways from curated databases and text-mining

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SP3 — SYT1

Text-mined interactions from Literome

Tsuda et al., Oncogene 2005 (Sarcoma, Synovial) : These results suggest that SYT-SSX1 is able to induce p21 in a manner independent on hBRM and p53 but dependent on Sp1/Sp3
Jutooru et al., J Biol Chem 2010 (Pancreatic Neoplasms) : Results of Sp1, Sp3, and Sp4 knockdown by RNA interference demonstrate that both p50 and p65 are Sp-regulated genes and that inhibition of constitutive or tumor necrosis factor induced NFkappaB by curcumin is dependent on down-regulation of Sp1, Sp3 , and Sp4 proteins by this compound