Takada et al., J Biol Chem 2004
:
PTD-p65-P1 had no effect on TNF induced AP-1 activation
Zhu et al., Int J Biochem Cell Biol 2012
(Bone Resorption) :
The RANKL stimulated mRNA expression of osteoclast related genes and transcription factors were also diminished by ISL. Mechanistically, ISL blocked the RANKL triggered RANK-TRAF6 association, phosphorylation of mitogen activated protein kinases ( MAPKs ), inhibitor of ?Ba ( I?Ba ) phosphorylation and degradation, nuclear factor-?B ( NF-?B ) p65 nuclear translocation, as well as activator protein (AP)-1 activation