◀ Back to PARP14
DIABLO — PARP14
Text-mined interactions from Literome
Guo et al., Blood 2002
:
While it had no activity alone, ectopic overexpression of
Smac/DIABLO or treatment with the N-terminus heptapeptide ( Smac-7 ) or tetrapeptide ( Smac-4 ) of Smac/DIABLO significantly
increased Epo B- or Apo-2L/TRAIL induced processing and
PARP cleavage activity of caspase-3
Colo et al., FEBS Lett 2007
(Leukemia, Myelogenous, Chronic, BCR-ABL Positive) :
In addition to the up-regulation of TRAIL receptors, the process involves Bid, caspases and
PARP activation , loss of mitochondrial membrane potential, and release of AIF, cytochrome c and
Smac/DIABLO to the cytoplasm