Gene interactions and pathways from curated databases and text-mining

◀ Back to NFKB1

NFKB1 — PPARD

Text-mined interactions from Literome

Rival et al., Eur J Pharmacol 2002 : PPARalpha and PPARdelta activators inhibit cytokine induced nuclear translocation of NF-kappaB and expression of VCAM-1 in EAhy926 endothelial cells
Planavila et al., Cardiovasc Res 2005 (Cardiomegaly) : Finally, coimmunoprecipitation studies showed that L-165041 strongly enhanced the physical interaction between PPARbeta/delta and the p65 subunit of NF-kappaB, suggesting that increased association between these two proteins is the mechanism responsible for antagonizing NF-kappaB activation by PPARbeta/delta activators ... These results suggest that PPARbeta/delta activation inhibits PE-induced cardiac hypertrophy and LPS induced NF-kappaB activation
Planavila et al., J Biol Chem 2005 (Hypertrophy) : Lipopolysaccharide stimulation of NF-kappaB in embryonic rat heart derived H9c2 myotubes, which only express PPARbeta/delta, caused both a reduction in Pdk4 expression and DNA binding activity of PPARbeta/delta to its response element, effects that were reversed by NF-kappaB inhibitors ... In hypertrophied hearts of banded rats the reduction in the expression of Pdk4 was accompanied by activation of NF-kappaB and enhanced interaction between p65 and PPARbeta/delta
Aarenstrup et al., J Invest Dermatol 2008 : In this article we further investigate the molecular mechanisms dictating the NF-kappaB dependent repression of PPARdelta in human keratinocytes
Rodríguez-Calvo et al., Diabetes 2008 : Because mitogen activated protein kinase-extracellular signal related kinase ( ERK ) 1/2 ( MEK1/2 ) is involved in LPS induced NF-kappaB activation in adipocytes, we explored whether PPARbeta/delta prevented NF-kappaB activation by inhibiting this pathway