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NFATC1 — NFKB1
Text-mined interactions from Literome
Takatsuna et al., J Bone Miner Res 2005
(Bone Resorption) :
The inhibition of NF-kappaB suppresses osteoclastogenesis by downregulation of NFATc1, suggesting that
NFATc1 expression is
regulated by
NF-kappaB in RANKL induced osteoclastogenesis
Zhang et al., Yao Xue Xue Bao 2005
(Brain Ischemia...) :
NFATc may be involved in calcineurin mediated ischemic brain damage and transcription factor
NF-kappaB may not be
involved
Huang et al., Cell Death Differ 2006
:
Osteoclast differentiation requires TAK1 and MKK6 for
NFATc1 induction and
NF-kappaB transactivation by RANKL
Yamashita et al., J Biol Chem 2007
:
NF-kappaB p50 and p52
regulate receptor activator of NF-kappaB ligand ( RANKL ) and tumor necrosis factor induced osteoclast precursor differentiation by activating c-Fos and
NFATc1
Kalliolias et al., Arthritis Rheum 2010
(Arthritis, Rheumatoid...) :
IL-27 inhibited human osteoclastogenesis, suppressed the induction of
NFATc1 , down-regulated the expression of RANK and triggering receptor expressed on myeloid cells 2 ( TREM-2 ), and
inhibited RANKL mediated activation of ERK, p38, and
NF-kappaB in osteoclast precursors