Gene interactions and pathways from curated databases and text-mining

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NFATC1 — NFKB1

Text-mined interactions from Literome

Takatsuna et al., J Bone Miner Res 2005 (Bone Resorption) : The inhibition of NF-kappaB suppresses osteoclastogenesis by downregulation of NFATc1, suggesting that NFATc1 expression is regulated by NF-kappaB in RANKL induced osteoclastogenesis
Zhang et al., Yao Xue Xue Bao 2005 (Brain Ischemia...) : NFATc may be involved in calcineurin mediated ischemic brain damage and transcription factor NF-kappaB may not be involved
Huang et al., Cell Death Differ 2006 : Osteoclast differentiation requires TAK1 and MKK6 for NFATc1 induction and NF-kappaB transactivation by RANKL
Yamashita et al., J Biol Chem 2007 : NF-kappaB p50 and p52 regulate receptor activator of NF-kappaB ligand ( RANKL ) and tumor necrosis factor induced osteoclast precursor differentiation by activating c-Fos and NFATc1
Kalliolias et al., Arthritis Rheum 2010 (Arthritis, Rheumatoid...) : IL-27 inhibited human osteoclastogenesis, suppressed the induction of NFATc1 , down-regulated the expression of RANK and triggering receptor expressed on myeloid cells 2 ( TREM-2 ), and inhibited RANKL mediated activation of ERK, p38, and NF-kappaB in osteoclast precursors