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CXCL16 — NFKB1

Text-mined interactions from Literome

Méndez-Samperio et al., J Interferon Cytokine Res 2002 : Finally, two specific NF-kappa B inhibitors, sulfasalazine and caffeic acid phenetyl ester ( CAPE ), strongly inhibited the production of CXCL-8 by human monocytes infected with M. bovis
Chandrasekar et al., J Biol Chem 2004 (Arteriosclerosis...) : However, treatment with pertussis toxin ( G ( i ) inhibitor ), wortmannin or LY294002 ( phosphatidylinositol 3-kinase ( PI3K inhibitors ) ), or Akt inhibitor or overexpression of dominant negative ( dn ) PI3K gamma, dnPDK-1, kinase-dead ( kd ) Akt, kdIKK-beta, dnIKK-gamma, dnI kappa B-alpha, or dnI kappa B-beta significantly attenuated CXCL16 induced NF-kappa B activation ... In conclusion, CXCL16 is a potent and direct activator of NF-kappaB and induces kappa B-dependent proinflammatory gene transcription ... CXCL16 mediated NF-kappa B activation occurred via heterotrimeric G proteins, PI3K, PDK-1, Akt, and I kappa B kinase (IKK)
Si et al., J Immunol 2004 (Acquired Immunodeficiency Syndrome) : Interestingly, although LPS induced IL-8/CXCL8 was dependent on NF-kappaB , the baseline or 15d-PGJ ( 2 ) -mediated IL-8/CXCL8 production was NF-kappaB independent
Cinatl et al., Int J Mol Med 2005 (Colonic Neoplasms...) : High hydrocortisone concentrations ( > or =50 microg/ml ) completely prevented increased DNA binding activity of AP-1 and NF-kappaB and inhibited up-regulation of CXCL8 and CXCL10, but did not reduce chemokine expression to basal levels
Keshamouni et al., Neoplasia (New York, N.Y.) 2005 (Carcinoma, Non-Small-Cell Lung...) : Similarly, an inhibitor of NF-kappa B activation ( PDTC ) also blocked CXCL8 , CXCL5, and CXCL1 production, consistent with their NF-kappa B-dependent regulation
Lehrke et al., J Am Coll Cardiol 2007 (Acute Disease...) : Endotoxin induction of CXCL16 in human macrophages was attenuated by aspirin, nuclear factor (NF)-kappa-B inhibition and peroxisome proliferator activated receptor ( PPAR)-gamma agonists
D'Aversa et al., J Neurosci Res 2008 (AIDS Dementia Complex...) : Gel shift analyses demonstrated that NFkappaB and AP-1, but not C/EBPbeta, mediate microglial CXCL8 production
Yang et al., Mol Immunol 2008 (Escherichia coli Infections...) : Bovine TLR2 and TLR4 properly transduce signals from Staphylococcus aureus and E. coli, but S. aureus fails to both activate NF-kappaB in mammary epithelial cells and to quickly induce TNFalpha and interleukin-8 ( CXCL8 ) expression in the udder
Bischoff et al., J Cell Biochem 2008 : NF-kappaB inhibition resulted in a decrease in CXCL8 levels in hMSCs grown in non-OGM
Martin et al., J Biol Chem 2009 : Furthermore, we identified the components of the CBM complex, Carma3, Bcl10, and Malt1, as key mediators of the CXCL8/IL8 induced NFkappaB activation and VEGF up-regulation
Ho et al., J Immunol 2009 : In contrast, NE did not induce NRF expression in A549 and Beas-2B cells, where NE only stimulates NF-kappaB activation and IL-8/CXCL8 induction
Khalaf et al., BMC immunology 2010 (Inflammation) : The present study shows that NF-kappaB regulated IL-6 but not CXCL8