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AIP — HSP90AA1

Pathways - manually collected, often from reviews:

• WikiPathways Aryl Hydrocarbon Receptor Pathway: Complex of SRC-AIP-AHR-HSP90AA1-PTGES3 → AHR (activation)
• WikiPathways Aryl Hydrocarbon Receptor: Complex of AIP-AHR-AIP-HSP90AA1-HSP90AA1 → CCL1 (mim-transcription-translation)
• WikiPathways Aryl Hydrocarbon Receptor: Complex of AIP-AHR-AIP-HSP90AA1-HSP90AA1 → CDC37 (activation) Enan et al., Biochem Pharmacol 1996*, Blankenship et al., Mol Pharmacol 1997*
• WikiPathways Aryl Hydrocarbon Receptor: Complex of AIP-AHR-AIP-HSP90AA1-HSP90AA1 → VEGFA (activation)
• WikiPathways Aryl Hydrocarbon Receptor: Complex of AIP-AHR-AIP-HSP90AA1-HSP90AA1 → ARNT/AHR (activation)
• WikiPathways Aryl Hydrocarbon Receptor: Complex of AIP-AHR → Complex of AIP-AHR-AIP-HSP90AA1-HSP90AA1 (activation)
  

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: AIP — HSP90AA1 (physical association, affinity chromatography technology) Schülke et al., PloS one 2010
• IRef Biogrid Interaction: AIP — HSP90AA1 (physical association, affinity chromatography technology) Kazlauskas et al., J Biol Chem 2000*
• IRef Biogrid Interaction: AIP — HSP90AA1 (direct interaction, pull down) Li et al., Nature structural & molecular biology 2011
• IRef Hprd Interaction: HSP90AA1 — AIP (in vivo) Laenger et al., FEBS Lett 2009*
• IRef Hprd Interaction: Complex of HSP90AA1-AIP-AHR-AHR-HSP90AA1-AIP-AIP-HSP90AA1-AHR (in vivo) Carver et al., J Biol Chem 1997*, Carver et al., J Biol Chem 1998*
• IRef Intact Interaction: Complex of 22 proteins (association, tandem affinity purification) Varjosalo et al., Nat Methods 2013

Text-mined interactions from Literome

Hollingshead et al., J Biol Chem 2004 : Finally XAP2 itself was capable of existing in multimeric complexes, and these complexes did not require Hsp90 or AhR to form
Laenger et al., FEBS Lett 2009 : The effect of XAP2 on GR requires its interaction with Hsp90 through the TPR motif