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IL6 — PON1
Text-mined interactions from Literome
Van Lenten et al., Circulation 2002
(Orthomyxoviridae Infections...) :
D-4F treatment increased plasma HDL cholesterol and
paraoxonase activity compared with PBS and
inhibited increases in LDL cholesterol and peak levels of
interleukin-6 after infection
Kumon et al., Life Sci 2003
:
To clarify this point, we evaluated the transcriptional
regulation of
PON1 gene by IL-1beta,
IL-6 and TNF-alpha in HepG2 cells using luciferase reporter gene assay
Ofek et al., J Mol Med (Berl) 2007
(Acute Disease...) :
Importantly,
IL-6 injected to young volunteers or administered in vitro to primary mononuclear blood cells
caused upregulation of AChE, but not BChE or
PON1 , excluding it from being the sole cause for this extended response