Gene interactions and pathways from curated databases and text-mining

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IL6 — PON1

Text-mined interactions from Literome

Van Lenten et al., Circulation 2002 (Orthomyxoviridae Infections...) : D-4F treatment increased plasma HDL cholesterol and paraoxonase activity compared with PBS and inhibited increases in LDL cholesterol and peak levels of interleukin-6 after infection
Kumon et al., Life Sci 2003 : To clarify this point, we evaluated the transcriptional regulation of PON1 gene by IL-1beta, IL-6 and TNF-alpha in HepG2 cells using luciferase reporter gene assay
Ofek et al., J Mol Med (Berl) 2007 (Acute Disease...) : Importantly, IL-6 injected to young volunteers or administered in vitro to primary mononuclear blood cells caused upregulation of AChE, but not BChE or PON1 , excluding it from being the sole cause for this extended response