Gene interactions and pathways from curated databases and text-mining

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SGCG — TNF

Text-mined interactions from Literome

Blalock et al., Invest Ophthalmol Vis Sci 2008 : Neutrophil elastase and TNF , present in higher amounts in the tears of patients with dry eye, may cause MAM release, allowing rose bengal staining
al-Daccak et al., Infect Immun 1994 (Arthritis, Infectious...) : In the present study, we have examined the ability of MAM to induce proinflammatory monokine ( interleukin 1 beta [IL-1 beta ] and tumor necrosis factor alpha [TNF-alpha ] ) gene expression in the THP-1 monocytic cell line ... Stimulation of the U937 monocytic cell line ( MHC class II-negative even after INF-gamma treatment ) with MAM did not induce either IL-1 beta or TNF-alpha transcription ... Finally, our results, obtained with protein tyrosine kinase inhibitors and antiphosphotyrosine Western blotting ( immunoblotting ), indicate that protein tyrosine kinase is involved in MAM induced IL-1 beta and TNF-alpha gene expression in the THP-1 monocytic cell line