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NEDD9 — TNF

Text-mined interactions from Literome

Beinke et al., J Biol Chem 2002 : Stimulation of cells with tumor necrosis factor alpha (TNFalpha) triggers NF-kappaB1 p105 proteolysis, releasing associated Rel subunits to translocate into the nucleus and modulate target gene expression ... Phosphorylation of serine 927 within the p105 PEST region by the IkappaB kinase (IKK) complex is required to promote p105 proteolysis in response to TNFalpha stimulation
Lang et al., Mol Cell Biol 2003 : In this study, TNF-alpha induced p105 proteolysis was revealed to additionally require the phosphorylation of serine 932
Tan et al., Biochim Biophys Acta 1994 : Our results indicate that both PAF and TNF stimulate the expression of NF-kappa B p50/p105 in vivo