UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

NCI Pathway Database FAS (CD95) signaling pathway: FASLG/FAS (trimer)/Src/Syk complex (FAS-FASLG-SRC-SYK) → SYK (SYK) (modification, collaborate) Beier et al., J Neurosci 2005, Letellier et al., Immunity 2010
Evidence: mutant phenotype, assay, physical interaction
NCI Pathway Database FAS (CD95) signaling pathway: FASLG/FAS (trimer)/Src/Syk complex (FAS-FASLG-SRC-SYK) → Src (SRC) (modification, collaborate) Beier et al., J Neurosci 2005, Letellier et al., Immunity 2010
Evidence: mutant phenotype, assay, physical interaction
NCI Pathway Database FAS (CD95) signaling pathway: FASLG/FAS (trimer)/Src/Syk complex (FAS-FASLG-SRC-SYK) → FASLG/FAS (trimer) complex (FAS-FASLG) (modification, collaborate)
Beier et al., J Neurosci 2005, Letellier et al., Immunity 2010
Evidence: mutant phenotype, assay, physical interaction
NCI Pathway Database FAS (CD95) signaling pathway: SYK (SYK) → FASLG/FAS (trimer) complex (FAS-FASLG) (modification, collaborate)
Beier et al., J Neurosci 2005, Letellier et al., Immunity 2010
Evidence: mutant phenotype, assay, physical interaction
NCI Pathway Database FAS (CD95) signaling pathway: FASLG/FAS (trimer)/Src/Syk complex (FAS-FASLG-SRC-SYK) → PI3K Class IA family (PIK3CA/PIK3R1/PIK3CB/PIK3R1) (modification, activates)
Beier et al., J Neurosci 2005, Letellier et al., Immunity 2010