Gene interactions and pathways from curated databases and text-mining

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FAS — MMP9

Text-mined interactions from Literome

Velthuis et al., J Biol Chem 2002 : bcl-2 overexpression could not prevent TRAIL induced mitochondrial dysfunction, whereas it completely prevented CD95L mediated loss of MMP and cytochrome c release
Watanabe et al., Biol Pharm Bull 2003 : The recruitment was blocked by a specific MMP-9 inhibitor, R94138, which did not affect the Fas mediated liver injury or induced expression of MMP-9
Ogier et al., BMC neuroscience 2005 : When compared to WT, mutant astrocytes displayed an overall increased constitutive gelatinase expression and were less responsive to Fas mediated upregulation of MMP-9 , of monocyte chemoattractant protein-1 ( MCP-1 ) and of intercellular cell adhesion molecule-1 ( ICAM-1 ), all markers of astrocyte inflammatory response