Gene interactions and pathways from curated databases and text-mining

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DDIT3 — FAS

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: DDIT3 → FAS (increases, FAS Activity, DDIT3 Activity) Brenner et al., J Biol Chem 1997*
    Evidence: In the present study, we show that Fas receptor ligation or cellular treatment with synthetic C6-ceramide results in activation or phosphorylation, respectively, of the small G-protein Rac1, Jun N-terminal kinase (JNK)/p38 kinases (p38-K), and the transcription factor GADD153