◀ Back to CCND1

CCND1 — NAB2

Text-mined interactions from Literome

Coradini et al., Cell Prolif 2000 (Adenocarcinoma...) : At inhibitory concentrations ( higher than 1 mM ) NaB reduced cyclin D1 and p53 level in a dose dependent manner and sustained the synthesis of p21waf1/cip1, probably in a p53 independent way, accounting for the G0/G1 block observed by flow cytometry
Li et al., Zhongguo Shi Yan Xue Ye Xue Za Zhi 2004 (Myelodysplastic Syndromes) : The results showed that NaB and/or ATRA blocked cells mainly in the G0/G1 phase of the cell cycle ; ATRA inhibited the mRNA expression of CDK6, CDK4, cyclin D3 and cyclin D1 ; NaB inhibited the mRNA expression of CDK2, cyclin D2 and cyclin D1 ; ATRA and NaB inhibited the mRNA expression of CDK6, CDK4, CDK2, cyclin D1, cyclin D2 and cyclin D3 ; ATRA and/or NaB both stimulated p21 expression at the mRNA levels