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UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

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PLAUR — RAC1

Text-mined interactions from Literome

Kjøller et al., J Cell Biol 2001 : In addition, a fourfold increase in the level of activated Rac is induced by uPAR expression
Jo et al., J Biol Chem 2003 : By contrast, Rac1 activation, which occurred as a result of uPAR overexpression, was EGFR independent
Eastman et al., Cell Signal 2012 : Autonomous ERK activation by uPAR requires H-Ras and Rac1
Rao et al., Oncogenesis 2013 : Further, s-uPAR induced Rac1 mediated cell migration while either function blocking uPAR antibodies or dominant negative mutant Rac1 expression in HUVECs mitigated s-uPAR enhanced cell migration