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MAP2K1 — PRKCA
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Pan et al., J Cell Physiol 2005
(Cardiomegaly) :
Stretch stimulated phosphorylation of
MEK1/ERK1/2 and MKK4/JNK was
inhibited by overexpression of DN
PKCalpha and delta, and that of MKK3/p38 inhibited by DN PKCdelta
Khundmiri et al., J Biol Chem 2005
(MAP Kinase Signaling System) :
Pharmacologic inhibition of
MEK-1 blocked PTH stimulated translocation of
PKCalpha , whereas transfection of constitutively active MEK-1 cDNA induced translocation of PKCalpha and increased phosphorylation of the Na+-K+-ATPase alpha1 subunit
Antoine et al., Endocrinology 1998
:
Insulin induction of
protein kinase C alpha expression is independent of insulin receptor Tyr1162/1163 residues and
involves mitogen activated protein kinase kinase 1 and sustained activation of nuclear p44MAPK