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FOS — VCAM1
Text-mined interactions from Literome
Cui et al., Zhonghua Jie He He Hu Xi Za Zhi 2002
(Asthma...) :
NF-kappa B and
AP-1 may
play important roles in the regulation of
VCAM-1 and eotaxin
Tsou et al., Toxicol Appl Pharmacol 2005
:
On the other hand, the TNF-alpha induced VCAM-1 expression could be completely abolished by inhibition of AP-1 or NF-kappaB activity, suggesting that activation of both
AP-1 and NF-kappaB was
necessary for
VCAM-1 expression
Lin et al., PloS one 2012
(Osteoarthritis) :
CCL2 mediated
VCAM-1 expression was
attenuated by CCR2 inhibitor ( RS102895 ), PKCd inhibitor ( rottlerin ), p38MAPK inhibitor ( SB203580 ), and
AP-1 inhibitors ( curcumin and tanshinone IIA )
Liu et al., Biochim Biophys Acta 2013
(Osteoarthritis) :
CCN4 induced
VCAM-1 expression was
attenuated by avß5 or a6ß1 integrin antibody, Syk inhibitor, PKCd inhibitor ( rottlerin ), JNK inhibitor ( SP600125 ), and
AP-1 inhibitors ( curcumin and tanshinone )
Udagawa et al., J Immunol 1996
:
Similar to expression of IL-2, we demonstrated that recombinant
vascular-cell adhesion molecule-1 , when co-immobilized with anti-CD3 mAb, significantly
enhanced the induction of transcription factors NF-AT,
AP-1 , and NF-kappa B as determined by electromobility shift assays
Ahmad et al., J Biol Chem 1998
:
Since c-Fos/c-Jun ( activating protein-1 (AP-1) ) are expressed in vascular endothelium during proinflammatory conditions, we investigated the
role of
AP-1 proteins in the expression of
VCAM-1 by TNF-alpha in SV40 immortalized human microvascular endothelial cells ( HMEC )