Nakayama et al., J Biochem 2010
:
Our previous study demonstrated that lipopolysaccharide (LPS) induced CHOP expression does not induce apoptosis, but activates a pro-IL-1beta activation process ... The induction of CHOP by LPS was delayed and weak, in comparison with CHOP induction by ER stress-inducer thapsigargin
Zeng et al., Arthritis Rheum 2011
(Spondylitis, Ankylosing) :
Although IFN? treatment up-regulated HLA-B expression ( 2-fold ; P < 0.0001 ), neither IFN? nor LPS substantially enhanced BiP or CHOP expression ( < 1.3-fold )
Esposito et al., American journal of physiology. Renal physiology 2013
(Acute Kidney Injury...) :
Since LPS directly increased CHOP in glomeruli and podocytes of WT mice, together these data suggest that the LPS induced increase of CHOP in kidneys may inhibit inflammatory response in renal cells and provide protection against AKI