Abend et al., J Virol 2010
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In a KS tumor derived endothelial cell line, the downregulation of TWEAKR by miR-K10a resulted in reduced levels of TWEAK induced caspase activation
Ikner et al., J Biol Chem 2011
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Knockdown of RIP1 by siRNA prevented TWEAK induced association of FADD with caspase-8 but not formation of the FN14-TRAF2-cIAP1 complex and inhibited apoptosis activation