Gene interactions and pathways from curated databases and text-mining

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INS — RAB10

Text-mined interactions from Literome

Sano et al., J Biol Chem 2003 : Insulin stimulated phosphorylation of a Rab GTPase activating protein regulates GLUT4 translocation
Matsumoto et al., Proc Natl Acad Sci U S A 2004 : Accordingly, Noc2 positively regulates insulin secretion from endocrine pancreas by inhibiting Gi/o signaling, and the interaction of Noc2 and Rab3 is required for the effect
Sano et al., Biochem J 2008 : Thus, if insulin increases the GTP form of Rab10 , the increase is limited to a small portion of the total Rab10
Sun et al., Proc Natl Acad Sci U S A 2010 : We conclude that Rab13 and Rab8A are Rab-GTPases activated by insulin , and that downstream of AS160 they regulate traffic of GLUT4 vesicles, possibly acting at distinct steps and sites
Chen et al., J Cell Biol 2012 : Rab10 and myosin-Va mediate insulin stimulated GLUT4 storage vesicle translocation in adipocytes
Sadacca et al., Mol Biol Cell 2013 : Insulin regulation of the pool of RAB10 required for GLUT4 translocation occurs through regulation of AS160, since activation of RAB10 by DENND4C, its GTP exchange factor, does not require insulin stimulation