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FST — GCG
Text-mined interactions from Literome
Mamin et al., Mol Endocrinol 2007
:
We show here that Activin A decreases
glucagon gene expression in the alpha-cell lines InR1G9 and alphaTC1 in a dose- and time dependent manner and that the effect is
blocked by
Follistatin
Zhang et al., Biochim Biophys Acta 1997
:
We also examined the
effects of transforming growth factor-beta ( TGF-beta ),
glucagon and alpha-adrenergic agonist, phenylephrine, on
follistatin mRNA levels ... TGF-beta increased the follistatin mRNA to levels similar to those caused by activin A. Phenylephrine and
glucagon also
increased follistatin mRNA levels but the effects were transient and weaker than those caused by activin A