Gene interactions and pathways from curated databases and text-mining

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ACE — IRF6

Text-mined interactions from Literome

Watanabe et al., J Cell Physiol 1992 : The LPS induced decrease in ACE activity was dependent on the concentrations of LPS ( IC50 = 15 ng/ml at 24 hr ) and was detectable at LPS concentrations as low as 1 ng/ml
Hagiwara et al., Intensive Care Med 2009 (Lung Injury...) : LOS also inhibited the LPS mediated decrease in angiotensin converting enzyme 2 (ACE2) activity ( p < 0.05 )
He et al., J Cell Mol Med 2013 : ChIP assay revealed that the acetylation of histone H4 (Ace-H4) decreased in the Thy-1 promoter region in response to LPS
Watanabe et al., Prostaglandins Leukot Essent Fatty Acids 1993 : We investigated the potency of various serotypes of lipopolysaccharides (LPS) by examining LPS induced stimulation of PGI2 production and suppression of ACE activity in cultured human umbilical vein endothelial cells ( HUVEC )
Kirkland et al., Infect Immun 1997 : Furthermore, in contrast to some other types of LPS with little activity, H. pylori LPS does not inhibit the CD14-70Z/3 cell response to E. coli LPS