Gene interactions and pathways from curated databases and text-mining

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CD79A — RAF1

Text-mined interactions from Literome

Abe et al., Ann N Y Acad Sci 2001 : A dominant negative Ras did not inhibit Bcr kinase activation, and overexpression of Bcr increased Ras/Raf-1 activity and DNA synthesis
Yu et al., Blood 2003 (Leukemia, Myelogenous, Chronic, BCR-ABL Positive) : These events were accompanied by down-regulation of the Raf-1/mitogen induced extracellular kinase ( MEK ) /extracellular signal related kinase ( ERK ) pathway as well as diminished expression of Bcr/Abl and cyclin D1, cleavage of p21CIP1 and phosphorylation of the retinoblastoma protein ( pRb ), and induction of the stress related kinases Jun kinase (JNK) and p38 mitogen activated protein kinase ( MAPK )