Nagata-Ohashi et al., J Cell Biol 2004
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A pathway of neuregulin induced activation of cofilin-phosphatase Slingshot and cofilin in lamellipodia
Sparrow et al., J Neurosci 2012
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These changes are associated with rapid membrane expansion yielding a 35-50 % increase in SC size within 30 min. Cofilin1-deficient SCs increase phosphorylation of ErbB2, ERK, focal adhesion kinase, and paxillin in response to NRG1 , but fail to increase in size possibly due to stabilization of unusually long focal adhesions