Gene interactions and pathways from curated databases and text-mining

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CD79A — TLR7

Text-mined interactions from Literome

Meiler et al., Allergy 2008 (Hypersensitivity) : These data suggest that T regulatory cells may contribute to the suppression of allergic diseases by suppression of IgE and induction of IgG4, whereas IgA production is enhanced by B-cell activation via TLR7 and TLR9
Bessa et al., J Immunol 2009 : Strikingly, both responses required TLR7 signaling, but systemic IgA depended upon TLR7 signaling directly to B cells whereas mucosal IgA required TLR7 signaling to lung dendritic cells and alveolar macrophages
Bessa et al., Immunol Invest 2010 (Infection) : T cell dependent and -independent IgA responses : role of TLR signalling ... Herein we review recent data, which points to a pivotal role of TLR signalling in controlling T-cell dependent and independent IgA responses both at mucosal and systemic levels