◀ Back to CD79A
CD79A — TLR7
Text-mined interactions from Literome
Meiler et al., Allergy 2008
(Hypersensitivity) :
These data suggest that T regulatory cells may contribute to the suppression of allergic diseases by suppression of IgE and induction of IgG4, whereas
IgA production is
enhanced by B-cell activation via
TLR7 and TLR9
Bessa et al., J Immunol 2009
:
Strikingly, both responses required TLR7 signaling, but systemic IgA depended upon TLR7 signaling directly to B cells whereas mucosal
IgA required
TLR7 signaling to lung dendritic cells and alveolar macrophages
Bessa et al., Immunol Invest 2010
(Infection) :
T cell dependent and -independent
IgA responses :
role of
TLR signalling ... Herein we review recent data, which points to a pivotal
role of
TLR signalling in controlling T-cell dependent and independent
IgA responses both at mucosal and systemic levels