Pathways - manually collected, often from reviews:
OpenBEL Selventa BEL large corpus:
CXCL8
→
FAS
(increases, CXCL8 Activity)
Evidence: To determine whether MCP-1 expression could be induced by standard pro-apoptotic stimuli relevant to SMC apoptosis in atherosclerotic lesions1, we treated low-passage human arterial SMCs with either recombinant Fas ligand (FasL), or activating anti-Fas antibody,plus 1.5 ?g/ml cycloheximide....Fig. 4a shows that by 24 h after treatment, MCP-1 transcript levels were highly upregulated by both anti-Fas and FasL. Release of IL-8 protein, as measured by enzyme-linked immunosorbent assay, was also upr...