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NOX4 — STAT3

Text-mined interactions from Literome

Al-Shabrawey et al., Invest Ophthalmol Vis Sci 2008 (Diabetes Mellitus, Experimental...) : These results suggest that simvastatin protects against the early signs of diabetic retinopathy by preventing NADPH oxidase mediated activation of STAT3
Souza et al., Toxicol Lett 2009 : NADPH oxidase and ERK1/2 are involved in cadmium induced-STAT3 activation in HepG2 cells
Li et al., Diabetes 2010 : Moreover, inhibition of Nox4 attenuated hypoxia induced upregulation of HIF-1alpha and high-glucose elicited phosphorylation of STAT3
Lee et al., Biochem Pharmacol 2013 : ATP stimulates PGE2/cyclin D1-dependent VSMCs proliferation via STAT3 activation : Role of PKCs dependent NADPH oxidase/ROS generation