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IFNA1 — IFNAR1

Pathways - manually collected, often from reviews:

• BioCarta ifn alpha signaling pathway: IFN-alpha/IFNAR1/IFNAR2/JAK1/TYK2 complex (IFNAR2-JAK1-IFNAR1-IFNA1-TYK2) → STAT1 (modification, activates)
• BioCarta ifn alpha signaling pathway: IFN-alpha/IFNAR1/IFNAR2/JAK1/TYK2 complex (IFNAR2-JAK1-IFNAR1-IFNA1-TYK2) → STAT2 (modification, activates)
• BioCarta ifn alpha signaling pathway: IFNAR2/TYK2 complex (TYK2-IFNAR2) → IFN-alpha/IFNAR1/IFNAR2/JAK1/TYK2 complex (IFNAR2-JAK1-IFNAR1-IFNA1-TYK2) (modification, collaborate)
  
• BioCarta ifn alpha signaling pathway: IFN-alpha/IFNAR1/IFNAR2/JAK1/TYK2 complex (IFNAR2-JAK1-IFNAR1-IFNA1-TYK2) → IFN-alpha (IFNA1) (modification, collaborate)
• BioCarta ifn alpha signaling pathway: IFN-alpha/IFNAR1/IFNAR2/JAK1/TYK2 complex (IFNAR2-JAK1-IFNAR1-IFNA1-TYK2) → IFNAR1/JAK1 complex (IFNAR1-JAK1) (modification, collaborate)
  
• BioCarta ifn alpha signaling pathway: IFN-alpha (IFNA1) → IFNAR1/JAK1 complex (IFNAR1-JAK1) (modification, collaborate)
  
• KEGG Natural killer cell mediated cytotoxicity: IFNA1/IFNA10/IFNA13/IFNA14/IFNA16/IFNA17/IFNA2/IFNA21/IFNA4/IFNA5/IFNA6/IFNA7/IFNA8/IFNB1/IFNG → IFNAR1/IFNAR2/IFNGR1/IFNGR2 (protein-protein, activation)
  
• KEGG Hepatitis C: IFNA1/IFNA10/IFNA13/IFNA14/IFNA16/IFNA17/IFNA2/IFNA21/IFNA4/IFNA5/IFNA6/IFNA7/IFNA8/IFNB1 → Complex of IFNAR1-IFNAR2 (protein-protein, activation)
• KEGG Measles: IFNA1/IFNA10/IFNA13/IFNA14/IFNA16/IFNA17/IFNA2/IFNA21/IFNA4/IFNA5/IFNA6/IFNA7/IFNA8/IFNB1 → IFNAR1/IFNAR2 (protein-protein, activation)
• KEGG Cytokine-cytokine receptor interaction: IFNA1/IFNA10/IFNA13/IFNA14/IFNA16/IFNA17/IFNA2/IFNA21/IFNA4/IFNA5/IFNA6/IFNA7/IFNA8 → Complex of IFNAR1-IFNAR2 (protein-protein, activation)
• Reactome Reaction: IFNA1 → IFNAR1 (indirect_complex) You et al., Mol Cell Biol 1999, Rani et al., J Biol Chem 1999, Mowen et al., Mol Cell Biol 2000, Myers et al., J Biol Chem 2001, Lamken et al., J Mol Biol 2004, Cajean-Feroldi et al., Biochemistry 2004, Roisman et al., J Mol Biol 2005, Geiger et al., J Virol 2006, Uzé et al., Curr Top Microbiol Immunol 2007, Xu et al., Frontiers in bioscience : a journal and virtual library 2008, Colamonici et al., Mol Cell Biol 1994, Improta et al., Proc Natl Acad Sci U S A 1994, Müller et al., Nature 1993, Yan et al., EMBO J 1996, Gauzzi et al., J Biol Chem 1996, Jiao et al., Mol Cell Biol 1996, Domanski et al., J Biol Chem 1997
• Reactome Reaction: IFNA1 → IFNAR1 (reaction) Rani et al., J Biol Chem 1999, Mowen et al., Mol Cell Biol 2000, Lamken et al., J Mol Biol 2004, Cajean-Feroldi et al., Biochemistry 2004, Roisman et al., J Mol Biol 2005, Geiger et al., J Virol 2006, Uzé et al., Curr Top Microbiol Immunol 2007, Colamonici et al., Mol Cell Biol 1994, Improta et al., Proc Natl Acad Sci U S A 1994, Müller et al., Nature 1993, Yan et al., EMBO J 1996, Gauzzi et al., J Biol Chem 1996, Domanski et al., J Biol Chem 1997

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Hprd Interaction: IFNA1 — IFNAR1 (in vitro) Uzé et al., J Mol Biol 1994*