Gene interactions and pathways from curated databases and text-mining

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NPPA — PRKCB

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: NPPA → PRKCB (increases, NPPA Activity)
    Evidence: To further assess the role of PKC in cardiac gene regulation, PKC expression vectors encoding constitutively activated PKC-alpha or PKC-beta, or a catalytically inactive PKC, were transiently cotransfected with the cardiac promoter/luciferase constructs. Cotransfection of either activated PKC-alpha or PKC-beta cDNA induces the expression of MLC-2 and ANF promoter/luciferase genes and of a reporter gene responsive to the transcription factor AP-1.