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MYC — TGFB1

Text-mined interactions from Literome

Ju et al., Cancer Lett 2003 (Stomach Neoplasms) : TGF-beta1 mediated down-regulation of c-Myc and induction of p21CIP1 were observed in SNU-620, but there was no change in SNU-216 in response to TGF-beta1
Mulder et al., Biochem Biophys Res Commun 1988 (Colonic Neoplasms) : We report for the first time that the proto-oncogene c-myc is repressed in response to transforming growth factor-beta in a human colon carcinoma cell line
Bang et al., J Biol Chem 1996 : TGF-beta1 increased the binding of p107 to the transcription factor E2F, leading to decreased c-Myc protein levels
Genestier et al., J Exp Med 1999 : In parallel, TGF-beta1 inhibited c-Myc expression in T cell hybridomas, and ectopic expression of a chimeric molecule composed of c-Myc and the steroid binding domain of the estrogen receptor ( Myc-ER ) blocked both the inhibition of FasL and the decrease of AICD induced by TGF-beta1, providing that 4-hydroxytamoxifen was present