Gene interactions and pathways from curated databases and text-mining

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BTK — IL7

Text-mined interactions from Literome

Middendorp et al., J Immunol 2002 (Agammaglobulinemia) : Furthermore, the absence of Btk resulted in increased proliferative responses to IL-7 in recombination activating gene-1-deficient pro-B cells ... These findings identify a novel role for Btk in the regulation of the differentiation stage-specific modulation of IL-7 responsiveness in pro-B and pre-B cells
Middendorp et al., J Immunol 2003 : Btk is involved in pre-B cell maturation by regulating IL-7 responsiveness, cell surface phenotype changes, and the activation of lambda L chain gene rearrangements