Gene interactions and pathways from curated databases and text-mining

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RAC1 — SDF2

Text-mined interactions from Literome

Bartolomé et al., Cancer Res 2004 (Lymphatic Metastasis...) : Moreover, SDF-1alpha triggered the activation of the GTPases RhoA, Rac1, and Cdc42 on BLM cells, and expression of dominant negative forms of RhoA and Rac1 , but not Cdc42, substantially impaired the invasion of transfectants in response to SDF-1alpha, as well as the increase in MT1-MMP expression
Fuhler et al., Blood 2008 (MAP Kinase Signaling System...) : Furthermore, SDF-1 stimulated activation of Rac and the PI3K target protein kinase B is impaired in CD34 ( + ) cells from MDS patients