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NEK3 — RAC1

Text-mined interactions from Literome

Miller et al., Mol Endocrinol 2005 (Breast Neoplasms) : Activation of guanosine triphosphatase Rac-1 in Chinese hamster ovary transfectants required both Nek3 and Vav2 and was inhibited by the overexpression of a kinase inactivating Nek3 mutant
Miller et al., Oncogene 2007 (Breast Neoplasms...) : In contrast, downregulation of Nek3 expression by small interfering RNA ( siRNA ) attenuated PRL mediated cytoskeletal reorganization, activation of GTPase Rac1 , cell migration and invasion of T47D cells