Gene interactions and pathways from curated databases and text-mining

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MAP2K6 — MAP3K13

Text-mined interactions from Literome

Tu et al., Cell Signal 2003 : They consist of a three-kinase module in which a mitogen activated protein kinase kinase kinase ( MAP3K ) activates a mitogen activated protein kinase kinase ( MAP2K ), which in turn activates MAPK
Huang et al., Biochem Biophys Res Commun 2003 : MAP3Ks are components of a three tiered protein kinase pathway in which a MAP3K phosphorylates and activates a mitogen activated protein kinase kinase ( MAP2K ), which in turn activates a mitogen activated protein kinase ( MAPK )
Pan et al., Mol Pharmacol 2007 : K252a have wide-range effects including Trk inhibition, MLK3 inhibition , and activation of phosphatidylinositol 3 kinase and mitogen activated protein kinase kinase signaling pathways through interactions with distinct targets and is a well known neuroprotective compound