Gene interactions and pathways from curated databases and text-mining

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ARSE — IL1A

Text-mined interactions from Literome

Soo Kim et al., J Ethnopharmacol 2012 : ASE also effectively suppressed the production of pro-inflammatory cytokines, tumor necrosis factor a, interleukin (IL)-1ß , and IL-6, and decreased the nuclear translocation and transactivity of activator protein-1 (AP-1) and NF-?B by inhibiting the phosphorylation of I?B-a in P. gingivalis LPS stimulated macrophage cells
Burger et al., J Clin Invest 1995 : The simultaneous presence of IL-1Ra and IL-1sRII abolished the IL-1 induced production of PGE2 and C'ase on both dermal fibroblasts and synovial cells, demonstrating that concurrently these two inhibitors are able to abolish most of the inflammatory response