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CCNG1 — IL7

Text-mined interactions from Literome

Moniuszko et al., J Virol 2004 (Lymphopenia) : Importantly, IL-7 induced cycling of both CD4+ and CD8+ central memory and effector memory T cells, demonstrating its contribution to the maintenance of the entire T-cell pool
Fry et al., J Immunol 2005 : Consistent with this, in normal hosts, IL-7 is required for survival of naive T cell populations, and IL-7 contributes to homeostatic cycling of naive and memory cells
Beq et al., Blood 2009 : Finally, we demonstrate that the IL-7 induced cell cycling is initiated within these organs before T cells migrate back into the bloodstream, indicating that T-cell homing is required for in vivo IL-7 function
Puronen et al., J Infect Dis 2012 (T-Lymphocytopenia, Idiopathic CD4-Positive) : Destabilization of p27 ( kip1 ), a critical step for IL-7 induced T-cell cycling , was decreased in patients with ICL, compared with controls ( P = .004 ), after IL-7 stimulation
Williams et al., Blood 1990 : Thymidine suiciding studies suggest that this targeted infection is due to specific induction of cycling of CFC-Pre-B by IL-7 and CFU-GM by IL-3
Soares et al., J Immunol 1998 : IL-7 prevented the decrease in Bcl-2 and Bcl-xL and induced cell cycling in up to 20 % of cord T cells after 8 days, resulting in a threefold increase in cord T cell numbers