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ANXA6 — LPA

Text-mined interactions from Literome

Huang et al., Arch Biochem Biophys 2000 : In this work, we examined possible interactions between the effects of EtOH and LPA on DNA synthesis, cell proliferation, activating phosphorylation of p44/p42 mitogen activated protein kinases ( MAPK ), and p70 S6 kinase (p70 S6K) activity ... In contrast, in the presence of zinc, EtOH enhanced the stimulatory effect of LPA on p70 S6K activity
Willard et al., Biochem Biophys Res Commun 2001 : We investigate, in this report, the mechanisms by which lysophosphatidic acid (LPA) activates p70 ( S6K ) ... Similarly, the effect of LPA on p70 ( S6K ) activity was antagonized by butan-1-ol but not butan-2-ol suggesting the involvement of agonist stimulated phospholipase D activity
Kam et al., FASEB J 2004 : We studied the role of PLD in the phosphorylation of p70 ( S6K ) and 4E-BP1 induced by lysophosphatidic acid (LPA) and platelet derived growth factor ( PDGF ) using fibroblasts deficient in PLD activity and also 1-butanol, which inhibits phosphatidic acid production by PLD ... Toxin B, which inactivates Rho GTPases, markedly impaired PLD1 activation and phosphorylation of Akt, p70 ( S6K ), and 4E-BP1 induced by LPA but had a minimal or no effect on the actions of PDGF