Gene interactions and pathways from curated databases and text-mining

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HES1 — TLR2

Text-mined interactions from Literome

Kapoor et al., J Immunol 2010 (Tuberculosis, Meningeal) : Further, CSL/RBP-Jk contributed to TLR2 mediated expression of MMP-9 or Hes1
Xie et al., Ann Clin Lab Sci 2010 (Endotoxemia) : The infusion of HES130/0.4 in endotoxemic rats, especially 15 ml/kg, significantly reduced the release of plasma TNF-alpha and IL-1beta, which was consistent with the observed inhibitory effects of HES130/0.4 on NF-kappaB activation, TLR4 mRNA expression, and TLR4 protein level in monocytes