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CCND1 — HMGB1
Text-mined interactions from Literome
He et al., Zhong Nan Da Xue Xue Bao Yi Xue Ban 2010
:
Compared with the control group,
HMGB1 at 10, 50, and 100 ng/mL obviously
increased HepG2 cells proliferation,
cyclin D1 and PCNA protein and mRNA expression after the treatment for 24 h, respectively ( P < 0.05 ) ...
Anti-HMGB1 significantly
inhibited the proliferation and
cyclin D1 and PCNA mRNA and protein expression of HMGB1 on HepG2 cells ( P < 0.05 )
Feng et al., J Cell Biochem 2012
(Lupus Nephritis) :
Inhibition of
HMGB1 by a specific short hairpin RNA vector
prevented cyclin D1/CDK4/p16 up-regulation and attenuated IFN-? induced MMC cell proliferation and PCNA ( proliferating cell nuclear antigen, PCNA ) expression