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MYLIP — SYT1
Text-mined interactions from Literome
Dai et al., Hum Reprod 2011
(Pre-Eclampsia) :
Both JunB/FosB and
p65 were
increased in placenta from women with severe pre-eclampsia versus a normal pregnancy, with elevated expression of
miR-155 ( P < 0.05 )
Ruan et al., Proc Natl Acad Sci U S A 2011
(Diabetes Mellitus, Type 1) :
In pancreatic ß cells, c-Rel and
p65 of the NF-?B family
activated the
mir21 gene promoter and increased miR-21 RNA levels ; miR-21 in turn decreased the level of PDCD4, which is able to induce cell death through the Bax family of apoptotic proteins
Scisciani et al., J Hepatol 2012
(Carcinoma, Hepatocellular...) :
Exogenously expressed
p65/RelA activates the
miR-224 promoter and a dominant negative form of I?Ba ( I?BSR ) represses it
Li et al., BMC molecular biology 2012
(Esophageal Neoplasms) :
Mutation two of these KB sites impaired
p65 induced
miR-34a transcriptional activity ... In addition, we found that overexpression of NF-kappaB
p65 could not successfully
induce miR-34a expression in esophageal cancer cell lines with mutant p53 or decreased p53