Pathways - manually collected, often from reviews:
OpenBEL Selventa BEL large corpus:
ADRBK1 (GRK2)
→
MDM2
(decreases, MDM2 Activity, GRK2 Activity)
Salcedo et al., EMBO J 2006* Evidence: We report that Mdm2, an E3-ubiquitin ligase involved in the control of cell growth and apoptosis, plays a key role in GRK2 degradation.