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IL10 — PDC
Text-mined interactions from Literome
Zou et al., Eur J Immunol 2001
(Adenovirus Infections, Human) :
Exogenous
IL-10 suppressed
PDC type I interferon secretion without reducing PDC viability ... Therefore, monocyte
IL-10 regulates
PDC type I interferon secretion, and PDC type I interferons inhibit MDC differentiation and function
Duramad et al., Blood 2003
:
As the activities of ISS on PDCs are central to many clinical applications of ISS, we have studied the
effects of
IL-10 on
PDC stimulation by 3 distinct classes of ISS
Janke et al., Immunology 2006
:
A similar T helper type 1 ( Th1 ) /Th2 pattern of cytokines was generated in both systems, but significantly higher levels of IL-3, IL-4 and
IL-10 were
induced by
PDC
Dolganiuc et al., J Immunol 2006
(Hepatitis C, Chronic...) :
We identified CD14+ monocytes as the source of TNF-alpha and
IL-10 in the HCV core
induced inhibition of
PDC IFN-alpha production