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GSK3B — JUN

Pathways - manually collected, often from reviews:

• NCI Pathway Database Integrin-linked kinase signaling: Gsk3beta (GSK3B) → JUN (dimer) complex (JUN) (modification, activates) Troussard et al., Mol Cell Biol 1999*, Troussard et al., Oncogene 2000*
  Evidence: mutant phenotype
• WikiPathways Insulin Signaling: GSK3B/AKT2/AKT1/SGK3/SGK1/GSK3A/PDPK1/SGK2 → SRF/ELK1/FOXO1/FOS/JUN/FOXO3/EGR1 (activation)
  

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Dip Interaction: GSK3B — JUN (physical association, biochemical) Boyle et al., Cell 1991*
• IRef Ophid Interaction: GSK3B — JUN (aggregation, interologs mapping) Brown et al., Bioinformatics 2005

Text-mined interactions from Literome

Ma et al., Cancer Res 2007 (Carcinoma, Basal Cell...) : Inhibition of GSK3beta activation significantly stimulated activator protein-1 (AP-1) activity
Larabee et al., Infect Immun 2008 : GSK-3beta inhibitors prevented declines in cellular levels of cyclin D1 and c-Jun following treatment of macrophages with ET