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FGF9 — SNAI2
Text-mined interactions from Literome
Katoh et al., Curr Pharm Biotechnol 2011
:
Because
FGF , Hedgehog, TGFß, and non-canonical WNT signals synergistically
induce EMT regulators, such as Snail ( SNAI1 ),
Slug ( SNAI2 ), TWIST, and ZEB2 ( SIP1 ), tumor-stromal interaction at the invasion front aids cancer stem cells to acquire more malignant phenotype
Lau et al., PloS one 2013
(Neoplasm Invasiveness...) :
Moreover,
FGF2 up-regulated
Slug and ZEB1 expression via the PI3K/Akt/mTOR and MAPK/ERK signaling pathways, respectively